Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay.
In today's episode, I will answer your question , the one centred around topic of the day-"How drugs are eliminated?"Then I will tell you the difference in terms Excretion and Elimination. I will then start off the talk with discussions about Presystemic metabolism or First pass metabolism. After deriving an equation about Hepatic Extraction Ratio, I will officially start my talks about topic of the day i.e. Introduction to Kinetics of drug elimination. I will be listing various major and minor routes of drug elimination, then I will be initially give full description of Biliary excretion.In this I will be laying special emphasis upon "Enterohepatic Cycling". Definition, essence, examples, features, mechanism, exceptions , all will be conveyed and explained nicely! I will be concluding today's talks with two phrases or words of wisdom, science and mathematics to solve day to day dilemmas ! To wrap up, until next time(A' la prochaine!).....
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